Analysis of the algorithm: From rankings to backup genes.

Ranking section

For each of the affected genes present in the list, a ranking with the score and percentile of every possible gene was obtained. Once this was done, the position for every known backup gene was obtained and the statistical descriptor of all the values calculated.

Table 1. Backup position values for every kernel and net before integration.

Net Kernel Elements Min Max Average Standard_Deviation
biological_process ct 2 0.131 0.869 0.5 0.369
biological_process el 2 0.119 0.893 0.506 0.387
biological_process ka 2 0.131 0.845 0.488 0.357
cellular_component ct 2 0.484 0.736 0.61 0.126
cellular_component el 2 0.451 0.714 0.582 0.132
cellular_component ka 2 0.462 0.703 0.582 0.121
molecular_function ct 2 0.09 0.393 0.242 0.152
molecular_function el 2 0.135 0.438 0.287 0.152
molecular_function ka 2 0.034 0.438 0.236 0.202
phenotype ct 4 0.03 0.931 0.337 0.354
phenotype el 4 0.04 0.782 0.334 0.293
phenotype ka 4 0.04 0.931 0.369 0.353

Table 2. Backup position values for every kernel after integration

Integration Kernel Elements Min Max Average Standard_Deviation
integration_mean_by_presence ct 2 0.055 0.925 0.49 0.435
integration_mean_by_presence el 2 0.1 0.36 0.23 0.13
integration_mean_by_presence ka 2 0.12 0.13 0.125 0.005